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KMID : 0603219960030010058
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Korean Journal of Rhinology
1996 Volume.3 No. 1 p.58 ~ p.65
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Efficacy of Topical Levocabastine in the Treatment of Allergic Rhinitis
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Min Yang-Gi
Lee Chul-Hee
Jung Ha-Won
Kim Chun-Dong
Seo Jung-Ho
Jang Duk-Hee
Lee Jeung-Gweon
Jeon Sea-Yuong
Jang Tae-Young
Lee Bong-Jae
Paik Seog-In
Chung Seung-Kyu
Dhong Hun-Jong
Rha Ki-Sang
Kwon Sam-Hyun
Roh Hwan-Jung
Lee Sang-Hag
Kim Ic-Tae
Kim Kyung-Soo
Kim Chang-Kyu
Yoo Young-Sam
Choi Young-Seok
Park Heon-Soo
Hong Nam-Pyo
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Abstract
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This study was carried out to evaluate the efficacy of levocabastine, a new topical antihistamine, in the treatment of allergic rhinitis. The total 264 child and adult patients with symptoms and signs of allergic rhinitis and positive skin reactions were included in this study. Nasal symptoms with a scale of 4 were recorded daily with diary cards for two weeks. The treatment efficacy were globally assessed at the end of clinical trials. The onset of symptom relief was observed within 15 minutes in 77% of patients. There was excellent or good symptomatic improvement in 61% of patients. The adverse effects were insignificant. The results of this study suggest that levocabastine may be effective in the treatment of allergic rhinitis without significant side effects.
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KEYWORD
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Levocabastine Allergic rhinitis Topical antihistamine.,
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